CYT1 — Arabidopsis thaliana

Summary

AT2G39770, also known as CYT1, VTC1, or GMP1, encodes a GDP-mannose pyrophosphorylase (EC 2.7.7.13) with GTP:mannose-1-phosphate guanylyltransferase activity, and is also associated with SUMO transferase and binding activities. This Arabidopsis thaliana gene is linked to ascorbate and vitamin C biosynthesis, mannose and GDP-mannose anabolism, and the xanthophyll cycle. It is associated with shoot and root growth, flowering time, chlorophyll and anthocyanin content, cellulose content, hydrogen peroxide levels, and sensitivity to ozone, UV-B light, submergence, salt, and ammonium. The gene is also associated with disease susceptibility to Alternaria brassicicola, pathogen resistance, leaf senescence, and stomatal opening. The protein localizes to the cytosol, cytoplasm, nucleus, and COP9 signalosome.