ESD6 — Arabidopsis thaliana

Summary

AT2G39810, also known as HOS1 and ESD6, encodes a protein with ELYS and zinc finger RING/FYVE/PHD domains that possesses multiple molecular functions including ubiquitin-protein transferase activity, core promoter sequence-specific DNA binding, histone deacetylase activity, red and far-red light photoreceptor activity, calcium-dependent protein serine/threonine kinase activity, and phosphorelay sensor kinase activity. In Arabidopsis thaliana, this gene is associated with the regulation of photomorphogenesis, far-red light signaling, photosynthesis light reactions, stomatal lineage progression, seed morphogenesis, nuclear division, meiosis, nucleocytoplasmic transport, strigolactone and phytoalexin biosynthesis, and responses to cold, paraquat, and diterpene. It localizes to the nuclear envelope, nucleolus, chloroplast envelope, mitochondria, cytosol, and several chromatin-modifying complexes including PRC2, Sin3-type, HDAC, and Cul4-RING E3 ubiquitin ligase complexes. The gene is linked to numerous agronomic traits including leaf area, chlorophyll content, inflorescence height, stem length, petal size, fruit position, tuber size, photoperiod sensitivity, and responses to cold, salt, drought, and pathogen stress. Related genes in other species are linked to cold stress tolerance.