COI1 — Arabidopsis thaliana

Summary

AT2G39940, known as COI1 (CORONATINE INSENSITIVE 1) in Arabidopsis thaliana, encodes an F-box protein containing a leucine-rich repeat domain and a transport inhibitor response domain. The product exhibits DNA binding, transcription factor binding, and transcription corepressor binding activities, and is localized to the SCF ubiquitin ligase complex. COI1 is associated with jasmonate perception and signaling, including jasmonate-mediated root growth inhibition, wound response, and defense against herbivory and fungal pathogens. The gene is linked to pollen fertility, silique development, and vegetative storage protein expression. Additional associations include regulation of secondary growth, indole glucosinolate metabolism, and responses to chemical stimuli. COI1 has been connected to traits such as leaf trichome density, floral organ number, and temperature stress response. Studies of related genes in other species link the COI1 family to disease tolerance in Fusarium and Verticillium.