ATX1 — Arabidopsis thaliana

Summary

AT2G31650 (ATX1, also known as SDG27) encodes a protein with histone H3K4 dimethylase, histone H3 methylase, histone H3K4 trimethylase, histone H3K36 methylase, histone H3K4 methylase, protein methylase, and histone methylase activities, classified as EC 2.1.1.354. The protein contains SET, PHD, PWWP and FY-rich domains, binds chromatin, histones, SUMO and phosphatidylinositol-5-phosphate, and localises to the nucleus, chromatin, cytosol and perinuclear region of cytoplasm. ATX1 is associated with regulation of inflorescence meristem size, stem cell differentiation, peptidyl-lysine methylation, copper ion transport and detoxification, carotenoid metabolism, TOR signalling, regulation of root morphogenesis, response to nitrate starvation, meristem determinacy, regulation of lateral root development, regulation of salinity response, and demethylation. Phenotypically, ATX1 is linked to plant development, gene expression, adaptation, stress adaptation, heat stress tolerance, and oxidative stress tolerance. The gene is also associated with traits including inflorescence size, floral organ size and number, leaf area index, silique fruit morphology, anther morphology, adventitious rootless, shoot axis branching, callus induction, germination rate, seed maturation, and sensitivity to copper, nitrogen, jasmonic acid and brassin