COP1 — Arabidopsis thaliana

Summary

AT2G32950, known as COP1 (CONSTITUTIVE PHOTOMORPHOGENIC 1) in Arabidopsis thaliana, encodes a RING-finger and WD40-repeat protein that functions as a ubiquitin ligase substrate adaptor and exhibits adenylyltransferase activity, and amino acid binding. COP1 is associated with photomorphogenesis, shade avoidance, phytochrome signaling, and phototransduction. It is linked to cotyledon opening, light-dependent seedling development, and abscisic acid signaling. The gene is connected to numerous agronomic traits including grain yield, panicle number, stem number, leaf area index, vegetative vigor, drought recovery, germination ratio, chlorophyll ratio, and responses to UV-A light, far-red light, and parasitic weeds. COP1 localizes to nuclear ubiquitin ligase complexes and is involved in jasmonate conjugation and HY5 degradation. Studies in related genes in other species link the COP1 family to grain yield in rice and disease resistance in tomato.