PIN1 — Arabidopsis thaliana

Summary

AT1G73590 (PIN1, PIN-FORMED 1) in Arabidopsis thaliana encodes an auxin efflux carrier, a transmembrane transporter that also exhibits inositol-1,4-bisphosphate 1-phosphatase activity, 3'(2'),5'-bisphosphate nucleotidase activity, and binds multiple phosphoinositides and clathrin. PIN1 is associated with polar auxin transport, vascular tissue formation and patterning, cotyledon vasculature formation, pavement cell morphogenesis, pollen grain development, interfascicular cambium development, shoot apex development, and vein density. It is linked to phyllotactic patterning, stem cell fate determination, transcytosis, clathrin-mediated endocytosis regulation, and membrane localization. The gene has been connected to traits including pistil size and length, root system depth, leaf morphology, carbon isotope discrimination, gravity response, inflorescence size, stamen number, seed set percent, leaf relative water content, manganese sensitivity, blue light sensitivity, brassinosteroid content, and temperature stress response. Studies of related genes in other species link the family to fruit development, parthenocarpy, flower abscission, and shoot architecture.