CLV1 — Arabidopsis thaliana

Summary

AT1G75820, designated CLV1 in Arabidopsis thaliana, encodes a leucine-rich repeat receptor-like kinase (LRR-RLK) with serine/threonine protein kinase activity. It is a transmembrane receptor protein kinase that exhibits peptide receptor activity and protein phosphatase activity. CLV1 is associated with shoot apical meristem stem cell maintenance, meristem development, and stem cell specification. The gene is linked to the regulation of stem cell proliferation, embryonic meristem development, and organ initiation. CLV1 has been connected to numerous developmental traits including floral organ size, carpel morphology, inflorescence development, fruit diameter, and phyllotaxy. It is also associated with stress responses, nitrate uptake, cytokinin content, and plant male sterility. The CLV1 protein localizes to the plasma membrane, endocytic vesicles, endoplasmic reticulum, Golgi, plasmodesmata, and apoplast. Studies of related genes in other species link the family to cell expansion.