APT2 — Arabidopsis thaliana

Summary

AT1G80050 (APT2) in Arabidopsis thaliana encodes adenine phosphoribosyltransferase 2, an enzyme with adenine phosphoribosyltransferase activity (EC 2.4.2.7) and phosphate transmembrane transporter activity. The protein belongs to the adenine phosphoribosyltransferase family and is localized to the cytosol, plasma membrane, and Golgi complex. APT2 is associated with adenine and AMP salvage, UMP and purine ribonucleoside salvage, pyrimidine nucleotide biosynthesis, phosphate ion membrane transport, phosphate homeostasis, glycan biosynthesis, mitotic cell cycle, cell death, programmed cell death, and DNA repair. The gene has been connected to cytokinin content and metabolism, as well as phosphate transport. Studies of related genes in other species link the family to miscellaneous traits and climatic phenotypes.