SOS1 — Arabidopsis thaliana

Summary

AT2G01980, known as SOS1 (Salt Overly Sensitive 1) in Arabidopsis thaliana, encodes a sodium/hydrogen exchanger (NHX7) belonging to the cation/H+ exchanger CPA1 family, with annotated sodium:hydrogen exchanger, sodium transporter, lithium:proton antiporter, and potassium:proton antiporter activities. SOS1 is associated with salt response, high-salinity stress tolerance, sodium homeostasis, and heat tolerance. It is linked to sodium uptake, sodium and potassium content, yield traits, germination rate, root length, chlorophyll content, photosynthetic rate, stomatal resistance, and transpiration rate. The protein localizes to the tonoplast, vacuolar membrane, endosome, and chloroplast envelope, and is associated with cell pH elevation, sodium ion membrane transport, regulation of ion transport, and phloem loading. Studies of related genes in other species connect the family to ion homeostasis, sodium exclusion, cadmium tolerance, and bacterial wilt resistance.