DRB1 — Arabidopsis thaliana

Summary

AT1G09700 (DRB1, also known as HYL1) in Arabidopsis thaliana encodes a protein with dsRNA-binding domains characteristic of the DRB family, and is annotated with RNA methyltransferase, dsRNA binding, siRNA binding, miRNA binding, RNA endonuclease, phosphatase, protein kinase, and DNA-binding transcription factor activities. It is associated with miRNA transcription and processing, including pri-miRNA and pre-miRNA processing, miRNA strand selection, and gene silencing by miRNA-directed mRNA cleavage. DRB1 is associated with thermomorphogenesis, regulation of adaxial/abaxial pattern formation, seed maturation, and cellulose microfibril organization. Phenotypically, it is associated with root system development, protein stability, and numerous traits including leaf morphology, floral organ number, vegetative vigor, viral disease response, heterosis, and glucose content. The protein localizes to D-bodies, nuclear speckles, stress granules, and the nucleolus.