B-1 — Arabidopsis thaliana

Summary

AT1G12110, also known as NRT1.1, NPF6.3 or CHL1, encodes a protein with nitrate transmembrane transporter activity, symporter activity, calcium-dependent protein serine/threonine kinase activity, and protein serine/threonine kinase activity. This transmembrane symporter belongs to the PTR2/POT family of the major facilitator superfamily. In Arabidopsis thaliana, NRT1.1 is associated with nitrate uptake and transport, nitrogen sensing, lateral root proliferation, and defense against necrotrophic fungi. The gene has been connected to drought tolerance, aluminum resistance, ammonium toxicity response, and growth under nitrogen deficiency. It localizes to the plasma membrane, plastid, mitochondria, cytosol, and nucleus. NRT1.1 is linked to abscisic acid-mediated signaling, responses to drought and salinity, and hormone metabolism. Related genes in other species associate it with stomatal closure and ATP signaling.