PHR1 — Arabidopsis thaliana

Summary

AT1G12370, known as PHR1 or UVR2, encodes a class 2 DNA photolyase with CPD photolyase activity, FAD binding, and DNA binding. This enzyme is associated with photoreactivation DNA repair and UV protection. PHR1 is associated with phosphate homeostasis, signaling, and starvation responses, as well as leaf senescence, flowering time, root hair density and length, anthocyanin content, and jasmonic acid content. It has been linked to drought tolerance, pathogen resistance, and high light stress tolerance. The protein localizes to the plastid, cytoplasm, and nucleus, and is associated with processes including nitrate assimilation, flavonoid metabolism, homologous recombination, and mitophagy. Studies of related genes in other species link the family to phosphorus deficiency tolerance, aluminum toxicity resistance, and arbuscular mycorrhizal symbiosis.