GN — Arabidopsis thaliana

Summary

AT1G13980, known as GNOM (GN), EMB30, MIZ2, or VAN7 in Arabidopsis thaliana, encodes a protein containing a Sec7 domain and a GBF1-like TPR domain, with annotated GTP:GDP antiporter activity, cis-trans proline isomerase activity, and protein homodimerization activity. GN is associated with endocytic recycling, vesicle formation, transcytosis, and regulation of ARF protein signal transduction, and localizes to the Golgi stack, endosome membrane, and secretory vesicle. The gene is linked to embryo patterning, cell polarity, cell adhesion, and cell expansion, as well as vasculature development, tropism, and response to gravity and water. Trait associations include phototropism, root development, auxin content, cytokinin sensitivity, seed dormancy, drought tolerance, and disease tolerance. Related genes in other species further connect the family to membrane trafficking and developmental processes.