FMO1 — Arabidopsis thaliana

Summary

AT1G19250 (FMO1) in Arabidopsis thaliana encodes a flavin-containing monooxygenase with pipecolic acid N-hydroxylase activity, N,N-dimethylaniline monooxygenase activity, and peptidyl-proline dioxygenase activity, and is associated with NADP and FAD binding. FMO1 is linked to the induction of programmed cell death, downregulation of photosynthesis, and systemic acquired resistance. It has been connected to disease resistance, antiviral resistance, bacterial resistance, and pathogen resistance, as well as systemic acquired acclimation and defense priming. The gene is associated with salicylic acid and camalexin biosynthesis, response to insects, and autophagy. FMO1 is also linked to traits including flowering time, abscisic acid content, aluminum response, ethylene sensitivity, stomatal resistance, and drought tolerance. It localizes to the nucleus and is involved in N-hydroxypipecolic acid biosynthesis and root meristem development.