AT1G25540 — Arabidopsis thaliana

Summary

AT1G25540, also known as PFT1 or MED25, encodes a mediator complex subunit containing a Med25 VWA domain and acts as a transcription coactivator with DNA-binding and protein homodimerization activity. It is associated with chromatin looping, thermomorphogenesis, regulation of sulfate assimilation, and positive regulation of photomorphogenesis. The gene is linked to resistance to viruses and defense responses against necrotrophic pathogens, as well as to traits including seed volume, seed protein content, inflorescence height, leaf area index, branch angle, shoot elongation under submergence, submergence tolerance, iron sensitivity, and nitrate sensitivity. It localizes to the nucleus, mediator complex, and Golgi apparatus. Related genes in other species are associated with virus tolerance.