PIN7 — Arabidopsis thaliana

Summary

AT1G23080 (PIN7) in Arabidopsis thaliana encodes an auxin efflux carrier, a member of the PIN-FORMED family, and also exhibits inositol-1,4-bisphosphate 1-phosphatase and 3'(2'),5'-bisphosphate nucleotidase activities, along with binding to various phosphoinositides and clathrin. PIN7 is associated with auxin efflux transmembrane transporter activity and is linked to embryonic pattern formation, flowering time, cell polarization, tropism, and regulation of endocytosis. It localizes to the basal plasma membrane, recycling endosome, and clathrin-coated vesicles. The gene is associated with numerous traits including root system depth, gravity response, phototropism, seed set, leaf vein morphology, shoot branching, and responses to blue light, aluminum, and manganese. PIN7 is also associated with pathways in auxin signalling, seed development, and clathrin-mediated endocytosis of PIN proteins.