PP2AA3 — Arabidopsis thaliana

Summary

AT1G13320 (PP2AA3) encodes a regulatory subunit A of protein phosphatase 2A (PP2A), a HEAT-repeat-containing scaffold protein that binds alpha- and beta-tubulin and exhibits protein deacetylase, tubulin deacetylase, and histone deacetylase activities. The gene is associated with regulation of phosphatase activity, protein deacetylation, tubulin deacetylation, preprophase band assembly, cortical cytoskeleton organization, and tropism. PP2AA3 has been linked to numerous agronomic traits including tiller angle, seed volume, specific leaf area, drought recovery, leaf water potential, stem length, brassinosteroid content, potassium uptake, and fruit quality. Phenotypic associations include microtubule organization, cell shape, root hair density, primary root length, lateral root number, auxin transport, phototropic responses, and photosynthesis. Studies of related genes in other species connect the PP2A regulatory subunit family to gravity response, leaf area index, stem diameter, and sugar content.