HSP70 — Sorghum bicolor

Summary

SORBI_3001G419200 (HSP70) in sorghum chromosome 1 encodes a heat shock protein 70, an ATP-dependent protein folding chaperone with ATP hydrolase activity and heat shock protein binding capability. This gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, response to virus, detoxification, protein breakdown, protein folding, pollen tube growth, programmed cell death, response to stress, response to heat, and cell death. It is associated with heat tolerance. The encoded protein localizes to the axonemal central pair projection, ER chaperone complex, ER lumen, chloroplast membrane, membrane, cytoplasm, and nucleus. Studies of related genes in other species, including BiP, BIP5, SCE70, HSP70, HSC-I, and HSC-2, link the family to similar chaperone functions.