G2 — Sorghum bicolor

Summary

SORBI_3001G453200 (SbG2) on sorghum chromosome 1 encodes a protein with domains characteristic of 3-ketoacyl-CoA synthases and polyketide synthases, and has been annotated with multiple enzyme activities including naringenin-chalcone synthase, acetoacetyl-CoA reductase, and trans-2-enoyl-CoA reductase (NADPH) activities. The gene is associated with very-long-chain fatty acid and wax biosynthesis, cutin-based cuticle development, suberin biosynthesis, pigmentation, UV protection, trichome papilla formation, and pollen tube development. It is linked to traits including drought tolerance, salt tolerance, high temperature stress response, oxidative stress response, abscisic acid sensitivity, flowering time, plant male sterility, leaf vein morphology, root morphology, and disease tolerance. The encoded protein is predicted to localize to the endoplasmic reticulum membrane, fatty acid elongase complex, cell wall, and chloroplast membranes. Studies of related genes in other species connect the family to cuticular wax production, very-long-chain fatty acid synthesis, and pollen fertility.