ADH — Sorghum bicolor

Summary

SORBI_3001G475800 (SbADH) encodes an enoyl reductase domain-containing protein with S-nitrosoglutathione reductase (NADH) and S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activities, classified as EC 1.1.1.1. It also exhibits aldo-keto reductase, redox, calcium ion binding, protein homodimerization, zinc binding, and protein binding activities. The gene is associated with responses to hypoxia, flooding, hydrogen peroxide, heat acclimation, sucrose, caffeine, and estradiol, as well as methanal metabolism and catabolism, cellular respiration, cell wall modification, seed development, programmed cell death, osmotic and salinity responses, and homeostasis. It localizes to plastids, mitochondria, cytosol, plasmalemma, cytoplasm, and nucleus. Associations include stem thickness, respiration rate, photosynthetic rate, plant height, leaf senescence, herbicide sensitivity, drought tolerance, salt tolerance, disease tolerance, and low temperature stress response. Phenotypes linked to the family include submergence, waterlogging, hypoxia, cold, and salt stress tolerance, aldehyde detoxification, fermentation, and stomatal closure.