CYP71E1 — Sorghum bicolor

Summary

SORBI_3002G110200, also known as CYP71E1, encodes an uncharacterized protein with a cytochrome P450 domain. It has 4-hydroxyphenylacetonitrile hydroxylase activity and 4-hydroxyphenylacetaldehyde oxime monooxygenase activity, and is associated with oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen, monooxygenase activity, iron binding, heme binding, and redox activity. This sorghum gene on chromosome 2 is associated with dhurrin anabolism, response to water, electron transport chain, electron transfer, alkaloid anabolism, syngamy, fruit ripening, detoxification, NO storage, photosynthetic electron transport chain, glucosinolate anabolism, and root development. The encoded protein localizes to the ER membrane and membrane. Related genes in other species connect the family to additional oxidoreductase activities (EC 1.14.14.37, 1.14.14.190), though these specific functions are not yet established in sorghum.