CYP — Sorghum bicolor

Summary

SORBI_3002G052700, designated SbSQN and also known as CYP, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) with a cyclophilin-type PPIase domain. The gene is associated with diverse molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, cyclosporin A binding, histone binding, chromatin binding, and calcium ion binding. It is linked to biological processes such as regulation of ARF protein signal transduction, auxin transport, embryonic pattern specification, alternative mRNA splicing, and activation of secondary metabolite biosynthesis. Associations with traits include variegated leaf, bacterial disease response, temperature stress response, starch grain synthesis, sucrose content, phototropism, root hair length, chloroplast development, jasmonic acid content, arsenic concentration, flowering time, and leaf senescence. The gene product localizes to the mitochondrial ribosomal small subunit, Golgi stack, multivesicular body, secretory vesicle, and stress granule. Studies of related genes in other species link the family to cold stress tolerance, hydrotropism, phototropism, apical-basal patterning, root development, and grain weight.