PPAR — Sorghum bicolor

Summary

SORBI_3002G101403 (symbol PPAR) on sorghum chromosome 2 encodes an uncharacterized protein with D-isomer-specific 2-hydroxyacid dehydrogenase catalytic and NAD-binding domains, and multiple annotated oxidoreductase activities including phosphoglycerate dehydrogenase, formate dehydrogenase, hydroxypyruvate reductase, glyoxylate reductase, and glycerate dehydrogenase activities. The gene is associated with photorespiration, the oxidative photosynthetic carbon pathway, formate breakdown, lipogenesis, and lipid metabolism. Its product localises to mitochondria and cytosol. Studies of related genes in other species link the family to phosphoglycerate dehydrogenase activity and several EC numbers (1.1.1.26, 1.1.1.28, 1.1.1.29, 1.1.1.79, 1.1.1.110, 1.1.1.237, 1.17.1.9).