PMIT1 — Sorghum bicolor

Summary

SORBI_3001G462500 (SbPMIT1) on sorghum chromosome 1 encodes a metal transporter of the NRAMP family, annotated with metal ion, manganese, iron, and cadmium transmembrane transporter activities. The gene is associated with manganese, iron, cadmium, and lead ion transport and homeostasis, as well as cellular responses to manganese and iron, thiamin metabolism, regulation of vacuolar transport, and positive regulation of reactive oxygen species metabolism. It is linked to vacuolar, trans-Golgi network, endosome, and plastid membranes. Associations include copper homeostasis, iron remobilization, manganese uptake and toxicity tolerance, aluminum sensitivity, seed germination, grain cadmium concentration, photosystem II activity, and root growth. Studies of related genes in other species connect the family to cadmium, cobalt, and aluminum accumulation, immunity, and grain yield traits.