HSP70 — Sorghum bicolor

Summary

SORBI_3001G419400 (HSP70) encodes an uncharacterized protein belonging to the Hsp70 family, with ATP-dependent protein folding chaperone activity, ATP hydrolase activity, heat shock protein binding, and ATP binding. In sorghum, this gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, response to virus, detoxification, protein breakdown, protein folding, programmed cell death, response to stress, response to heat, and cell death. It is linked to heat tolerance. The encoded protein localises to the ER chaperone complex, ER lumen, chloroplast membrane, membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species connect the family to similar chaperone functions.