HSP70 — Sorghum bicolor

Summary

SORBI_3001G419300 (HSP70) on sorghum chromosome 1 encodes a heat shock protein 70, an ATP-dependent protein folding chaperone with ATP hydrolase activity and heat shock protein binding capacity. This gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, detoxification, protein breakdown, and responses to virus, stress, and heat. It is linked to pollen tube growth, programmed cell death, and cell death. The encoded product localizes to the ER lumen and chaperone complex, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. HSP70 is associated with heat tolerance. Studies of related genes in other species, including BiP, BIP5, SCE70, and HSC-I/HSC-2, connect the family to similar chaperone functions.