HSP70 — Sorghum bicolor

Summary

SORBI_3001G419000 (HSP70) on sorghum chromosome 1 encodes a heat shock protein 70, a chaperone with ATP-dependent protein folding activity and ATP hydrolase activity, and is annotated as binding heat shock proteins. This gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, and response to virus, as well as detoxification, protein breakdown, programmed cell death, and cell death. It is linked to response to stress and heat, and to heat tolerance. The encoded protein localises to the ER chaperone complex, ER lumen, chloroplast membrane, membrane, cytoplasm, and nucleus, and also to the axonemal central pair projection. Studies of related genes in other species link the HSP70 family to similar chaperone functions.