HSP70 — Sorghum bicolor

Summary

SORBI_3001G418600 (SbHSP70) on sorghum chromosome 1 encodes an uncharacterized protein with domains of the Hsp70 family, including ATPase_NBD, and has ATP-dependent protein folding chaperone activity, heat shock protein binding, ATP hydrolase activity, and ATP binding. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, response to virus, detoxification, protein breakdown, programmed cell death, response to stress and heat, and cell death. It has been linked to heat tolerance and photosynthetic rate. The encoded protein localises to the ER chaperone complex, ER lumen, chloroplast membrane, cytoplasm, nucleus, and axonemal central pair projection. Studies of related genes in other species link the HSP70 family to drought tolerance, grain yield, plant height, chlorophyll content, water use efficiency, stem rust and stripe rust resistance, heterosis, and various growth and biomass traits.