M2 — Nicotiana attenuata

Summary

A4A49_60110 (NaM2) on coyote tobacco chromosome 7 encodes a cyclophilin-type peptidylprolyl isomerase (PPIase) with cis-trans proline isomerase activity, and is also annotated for peroxidase activity, L-serine O-acetyltransferase activity, and salicylic acid binding. The gene is associated with nicotine metabolism, cysteine anabolism, the MEP pathway, protein proline isomerization, and responses to chlorate and sulfate starvation. It has been linked to numerous traits including leaf length, photosynthetic rate, respiration rate, starch grain synthesis, sucrose content, jasmonic acid content, protein content, herbicide sensitivity, zinc sensitivity, temperature stress response, phototropism, root hair length, and chloroplast development. Localization evidence connects the product to the thylakoid lumen, Golgi stack, secretory vesicle, and proteasome. Related genes in other species are linked to water stress tolerance, cold stress response, hydrotropism, and phototropism.