CAD — Nicotiana attenuata

Summary

A4A49_61173 (CAD) in coyote tobacco (Nicotiana attenuata) encodes a cinnamyl-alcohol dehydrogenase-like protein with oxidoreductase activity acting on CH-OH groups using NAD or NADP, and exhibits geraniol, vomilenine, mannitol, 8-hydroxygeraniol, and cinnamyl-alcohol dehydrogenase activities, along with metal and zinc binding. This gene is associated with oviposition, glycan biosynthesis, primary metabolism, pigmentation, phenylpropanoid metabolism, photorespiration, detoxification, lignin and flavonoid anabolism, alkaloid metabolism, and carbohydrate metabolism. It is linked to cytoplasmic localisation and has been connected to starch mobilization and lignin content. Related genes in other species link the broader CAD family to cinnamyl-alcohol dehydrogenase and mannitol dehydrogenase activities.