MEO — Nicotiana attenuata

Summary

A4A49_61900 (MEO, also known as ASK11) in coyote tobacco (Nicotiana attenuata) encodes a SKP1-like protein containing Skp1 component dimerisation and POZ domains. The gene product is associated with MAPK phosphatase activity, cullin family protein binding, auxin receptor activity, and blue light photoreceptor activity, among numerous molecular functions. It has been linked to SCF complex assembly, regulation of gibberellic acid-mediated signalling, acropetal auxin transport, and negative regulation of cytokinin signalling. Associations with agronomically relevant traits include rice thrips damage response, bacterial blight disease resistance, submergence tolerance, plant male sterility, seed oil content, drought tolerance, and heat and cold stress tolerance. The protein localises to the nuclear ubiquitin ligase complex, male germ cell nucleus, and pollen tube. Related genes in other species link the family to SCF-dependent proteasomal ubiquitin-dependent protein breakdown.