ACT — Nicotiana attenuata

Summary

A4A49_60853 (ACT1) on coyote tobacco chromosome 9 encodes an actin protein, a structural constituent of the cytoskeleton with ATPase and hydrolase activity, and binds actin, profilin, phospholipids, protein kinases, and copper. It is associated with actin filament-based processes including nucleation, stabilization, depolymerization, and capping, as well as cytoskeleton organization, cell tip growth, nuclear movement, karyogamy, Golgi-to-plasma membrane transport, and response to nutrient. The gene is linked to numerous traits including seed morphology and yield, leaf area, vegetative vigor, shoot branching, root hair length, water stress and osmotic response, nitrogen, potassium and magnesium sensitivity, aphid response, powdery mildew disease response, iron concentration, cytokinin content, brassinosteroid and ethylene sensitivity, and cell cycle and cell elongation traits. It localizes to the actin cytoskeleton, Golgi membrane, endosome, chloroplast envelope, and the Cul4-RING E3 ubiquitin ligase and Arp2/3 protein complexes.