M2 — Nicotiana attenuata

Summary

A4A49_61042, designated NaM2 in coyote tobacco (Nicotiana attenuata) on scaffold02553, encodes a cyclophilin-type peptidylprolyl cis-trans isomerase (PPIase) with annotated enzyme activity (EC 5.2.1.8) and additional molecular functions including salicylic acid binding, peroxidase activity, and L-serine O-acetyltransferase activity. This gene is associated with diverse biological processes such as nicotine metabolism, cysteine anabolism, the methylerythritol phosphate (MEP) pathway, and responses to chlorate and sulfate starvation. NaM2 is linked to numerous traits, including leaf length, sucrose content, jasmonic acid content, photosynthetic rate, respiration rate, starch grain synthesis, chloroplast development, and responses to temperature stress, light intensity, and herbicides. It is also connected to phenotypes such as heat stress tolerance, pathogen defense, disease resistance, and root hydrotropism. Studies of related genes in other species link the family to water stress tolerance, cold stress response, and drought response.