FLS2 — Nicotiana attenuata

Summary

A4A49_60395 (FLS2) in coyote tobacco (Nicotiana attenuata) encodes a leucine-rich repeat receptor-like kinase (LRR-RLK) with protein serine/threonine kinase activity, ATP binding, and signaling receptor activity. It is associated with steroid and SNARE binding, protein heterodimerization and homodimerization, and detection of brassinosteroid stimulus. The gene is linked to defense responses, including activation of defense against bacteria and upregulation of defense response, as well as viral translation and virus-induced post-transcriptional gene silencing. It is associated with floral organ development, regulation of floral meristem size, anther wall tapetum development, megasporogenesis, microsporogenesis, and gametophyte development. Additional associations include endocytosis, membrane fission, microtubule bundling, skotomorphogenesis, and regulation of cell growth. The product localizes to the plasma membrane, ER membrane, endosome, and nucleus. Studies of related genes in other species link the family to immune signaling and developmental regulation.