PAT — Nicotiana attenuata

Summary

A4A49_57891 (PAT, RUB2) in coyote tobacco (Nicotiana attenuata) encodes a Nedd8-like ubiquitin-like modifier with ubiquitin-like modifier activating enzyme activity and protein tag function. It is associated with protein neddylation, SCF complex assembly, modification-dependent proteolysis, and the proteasomal pathway. The gene is linked to cellular auxin homeostasis, jasmonic acid signaling, ethylene anabolism, response to red/far-red light, and regulation of circadian rhythm. Associations include leaf morphogenesis, endosperm development, phloem/xylem histogenesis, and flower development. It localizes to CRL and ubiquitin ligase complexes, cytosol, and ER. The gene is associated with biomass yield, shoot branching, flowering time, disease tolerance, herbicide sensitivity, and traits including leaf vein morphology, trichome morphology, and phototropism response.