FLS2 — Nicotiana attenuata

Summary

A4A49_55819 (FLS2) in coyote tobacco (Nicotiana attenuata) encodes a receptor serine/threonine kinase with ATP-binding activity, belonging to the leucine-rich repeat (LRR) domain superfamily and the StomDev_PlantInt_Reg family. The gene is associated with pattern-triggered immunity (PTI) signaling, activation of innate immune responses, and defense responses to parasitic plants and bacteria. It is linked to viral translation, membrane fission, endocytosis, and virus-induced post-transcriptional gene silencing. Associations also include heat acclimation, regulation of cell growth, megasporogenesis, microsporogenesis, anther wall tapetum development, and post-embryonic development. The encoded protein localizes to the plasma membrane, endoplasmic reticulum membrane, perinuclear ER, cortical ER, and nucleus. Studies of related genes in other species link the family to immune receptor signaling.