HA1 — Nicotiana attenuata

Summary

A4A49_57043 (HA1, also known as PMA1) in coyote tobacco (Nicotiana attenuata) encodes a P-type ATPase (EC 7.1.2.1) with cation-transporting, proton-transporting, and P-type ATPase activities, along with annotations for guanylyl cyclase, peptide receptor, and voltage-sensitive potassium channel activities. The gene is associated with proton export across the plasma membrane, vacuolar acidification, cell pH regulation, nitrate import, TOR signaling, very-long-chain fatty acid metabolism, proanthocyanidin anabolism, and response to pH and calcium ions. It has been linked to traits including alkali soil sensitivity, stamen number and length, pistil morphology, iron and manganese sensitivity, water stress and bacterial disease response, photosynthetic rate, stomatal closure, root and shoot development, leaf senescence, and auxin and brassinosteroid sensitivity. Localization evidence connects the product to the plasma membrane, tonoplast, ER, nuclear envelope, and plant-type cell wall.