ARF — Nicotiana attenuata

Summary

A4A49_56393 (ARF) in coyote tobacco (Nicotiana attenuata) encodes a small GTPase of the ARF family, with annotated molecular functions including G protein activity, phosphatidylinositol kinase activity, and phospholipase activator activity. The gene is associated with vesicle-mediated transport to the plasma membrane, ER-to-Golgi transport, and Golgi organization. It is linked to nicotine and alkaloid anabolism, regulation of auxin metabolism, and blue light signaling. Associations with agronomically relevant traits include biomass yield, water use efficiency, days to flowering, leaf senescence, stomatal resistance, and responses to low temperature, oxidative stress, and abscisic acid. The gene is also associated with phototropism, root and shoot development, and viral disease response. Studies of related genes in other species link the ARF family to fruit development, stress tolerance, and vesicular transport.