ACT — Nicotiana attenuata

Summary

A4A49_52227 (ACT, AC101) in coyote tobacco (Nicotiana attenuata) encodes a protein with an ATPase_NBD domain and multiple molecular functions including actin, phospholipid, profilin, and F-actin binding, structural constituent of the cytoskeleton, protein serine/threonine phosphatase activity, and hydrolase activity. The gene is associated with actin cytoskeleton organization, actin filament stabilization and depolymerization, cell tip growth, cytoskeleton organization, and pronuclear migration. It is linked to numerous agronomically relevant traits including seed yield, leaf area, vegetative vigor, water stress response, nitrogen and potassium sensitivity, shoot axis branching, root hair length, trichome morphology, aphid response, wheat powdery mildew disease response, and osmotic response sensitivity. Localization associations include the actin cytoskeleton, Golgi membrane, endosome, chloroplast envelope, and the Cul4-RING E3 ubiquitin ligase complex.