CHS — Nicotiana attenuata

Summary

A4A49_38673 (CHS) on chromosome 3 of coyote tobacco (Nicotiana attenuata) encodes a chalcone synthase, a type III polyketide synthase with naringenin-chalcone synthase activity. The gene is associated with flavonoid and anthocyanin biosynthesis, secondary metabolism, pigmentation, and polyketide anabolism. It has been connected to flower color, anthocyanin and flavonoid content, seed size, and drought tolerance. Additional associations include pistil and fruit development, leaf development, pollen germination, regulation of flower development, auxin biosynthesis, and post-transcriptional gene silencing (PTGS) including virus-induced PTGS. The encoded protein is localized to the endoplasmic reticulum and exhibits acyltransferase and protein homodimerization activities. Studies of related genes in other species link the family to EC 2.3.1.74 (chalcone synthase).