MEO — Nicotiana attenuata

Summary

A4A49_39093 (MEO, also known as SKP1A) encodes a SKP1-like protein containing Skp1 component dimerisation and POZ domains, and is annotated with diverse molecular functions including cullin family protein binding, auxin receptor activity, and MAPK phosphatase activity. In coyote tobacco (Nicotiana attenuata), this gene is associated with SCF complex assembly, regulation of gibberellic acid-mediated signalling, acropetal auxin transport, and negative regulation of cytokinin signalling. It is linked to numerous agronomically relevant traits including seedling vigour, submergence tolerance, bacterial blight disease resistance, plant male sterility, photoperiod-sensitive flowering time, seed oil content, and drought tolerance. The gene product localises to nuclear ubiquitin ligase complexes, the proteasome core complex, and male germ cell nuclei. Studies of related genes in other species connect the SKP1 family to jasmonate perception, floral organ development, and defence against necrotrophic pathogens.