NIC1 — Nicotiana attenuata

Summary

A4A49_39854 (NIC1) on coyote tobacco chromosome 5 encodes a protein with an isochorismatase-like domain and nicotinamidase activity. The gene is associated with response to nicotine, nicotine metabolism, pyridine nucleotide salvage, polyamine metabolism, nicotine anabolism, alkaloid anabolism, innate immunity, response to abscisic acid, and signal transduction. It has been linked to respiration rate and salt stress tolerance. The product localises to the cytoplasm and nucleus. Studies of the Arabidopsis relative NIC1 connect the family to NAD biosynthesis and root growth, while sequence similarity links the family to days to flowering, root thickness, abscisic acid sensitivity, and salt tolerance.