ERF1 — Nicotiana attenuata

Summary

A4A49_40351 (ERF1B) in coyote tobacco (Nicotiana attenuata) encodes an AP2/ERF domain-containing transcription factor with DNA-binding and transcription coactivator activity. This gene is associated with diverse biological processes including phytoalexin and nicotine biosynthesis, trichome formation, ethylene signaling, and responses to drought, salinity, and light. It has been linked to traits such as hydrogen peroxide content, heterosis, photosynthetic rate, flowering time, and disease tolerance. Phenotypic associations include resistance to Botrytis cinerea and necrotrophic pathogens, heat, salt, and drought tolerance, as well as effects on stomatal aperture, lateral root development, and ethylene signaling. Studies of related genes in other species connect the family to ethylene response, GCC box-dependent transcription, and resistance to Pseudomonas syringae, Fusarium oxysporum, and viruses.