LPP1 — Nicotiana attenuata

Summary

A4A49_40001 (LPP1) in coyote tobacco (Nicotiana attenuata) encodes a protein with phosphatidate phosphatase and acid phosphatase activities, belonging to the PAP-like and PAP2/HPO domain families. This gene is associated with phospholipid dephosphorylation, flavonoid and phenylpropanoid metabolism, anthocyanin anabolism, alkaloid anabolism, and secondary metabolism. It is linked to viral spread within multicellular host, plasmodesma-mediated cell-to-cell transport, response to virus and UV-B, cellular response to hypoxia, leaf development, and ABA signaling. The encoded protein localizes to the plant-type cell wall, plasmodesma, membrane, plasmalemma, and cytoplasm. Associations with photosynthetic rate, chlorophyll content, disease tolerance, seed dormancy, carbon metabolism, bolting time, seed yield, plant growth, flowering time, and sugar content have been noted. Studies of related genes in other species link the family to phosphorus utilization, tuber development, anthocyanin production, and pathogen susceptibility.