ARF — Nicotiana attenuata

Summary

A4A49_39375 (ARF) in coyote tobacco (Nicotiana attenuata) encodes a small GTPase of the ARF family, with annotated molecular functions including G protein activity, phosphatidylinositol kinase activity, and phospholipase activator activity. The gene is associated with vesicle-mediated transport to the plasma membrane, ER-to-Golgi transport, and Golgi organization. It is linked to nicotine and alkaloid anabolism, anthocyanin biosynthesis, and regulation of auxin metabolism. Associations with agronomic traits include biomass yield, water use efficiency, days to flowering, stomatal resistance, leaf senescence, and responses to low temperature, oxidative stress, and abscisic acid. The gene is also associated with phototropism, blue light sensitivity, and viral disease response. Related genes in other species link the family to vesicular transport, phototropic responses, and stomatal aperture regulation.