PCS1 — Nicotiana attenuata

Summary

A4A49_38921 (PCS1) in coyote tobacco (Nicotiana attenuata) on scaffold05688 encodes an aspartic endopeptidase with a pepsin-like domain, belonging to the peptidase A1 family. The gene is associated with phytochelatin anabolism, cellular detoxification, and response to cadmium, as well as regulation of programmed cell death, hypersensitivity, and defense response. It is linked to proteolysis, homeostasis, and cell death processes. The encoded protein is localized to the apoplast, endoplasmic reticulum, and extracellular space. Studies of related genes in other species link the family to drought tolerance and classify it as an aspartic proteinase (EC 3.4.23.12).