PAT — Nicotiana attenuata

Summary

A4A49_38724 (PAT, also known as VAS1, NaVAS1, NaISS1, ISS1) in Nicotiana attenuata on chromosome 8 encodes a pyridoxal phosphate-dependent aminotransferase with multiple transaminase activities, including methionine-oxo-acid, nicotianamine aminotransferase, and 1-aminocyclopropane-1-carboxylate synthase activity. The gene is associated with inhibition of IAA biosynthesis, negative regulation of ethylene biosynthesis, tyrosine breakdown, methionine metabolism, L-phenylalanine anabolism, fermentation, shade avoidance, auxin and ethylene anabolism, fruit ripening, and cell death. It localizes to mitochondria and cytosol. The gene is linked to IAA content and auxin biosynthesis, ethylene biosynthesis, indole-3-acetic acid production, tryptophan homeostasis, and aromatic amino acid homeostasis. Related genes in other species are linked to chilling stress response, harvest index, cytoplasmic male sterility, and amino acid and sugar content.