CAD — Nicotiana attenuata

Summary

A4A49_38785 (CAD) in coyote tobacco (Nicotiana attenuata) on scaffold05306 encodes a CAD-like protein with zinc-binding and NAD(P)-dependent oxidoreductase activity, specifically annotated for geraniol, 8-hydroxygeraniol, vomilenine, mannitol, and cinnamyl-alcohol dehydrogenase activities. The gene is associated with multiple metabolic processes including phenylpropanoid, lignin, flavonoid, alkaloid, and carbohydrate metabolism, as well as pigmentation, photorespiration, detoxification, glycan biosynthesis, and primary metabolism. It is also linked to oviposition and localised to the cytoplasm. Associations with starch mobilization and lignin content have been noted. Studies of related genes in other species connect the family to EC numbers 1.1.1.183, 1.5.1.32, 1.1.1.324, 1.1.1.255, 1.1.1.195, and 1.3.1.-.