AGO2 — Nicotiana attenuata
Summary
A4A49_38573 (AGO2) on chromosome 2 of coyote tobacco (Nicotiana attenuata) encodes an Argonaute family protein containing Piwi, PAZ and RNaseH-like domains, with siRNA binding and RNA endonuclease activity. The gene is associated with posttranscriptional gene silencing, RNA processing, maintenance of shoot apical meristem identity, stem cell population maintenance, leaf development, and responses to jasmonic acid, bacteria and viruses. It has been linked to antiviral defense, virus and viroid resistance, antibacterial immunity, systemic acquired resistance, DNA damage response, epigenetic silencing, DNA methylation, transformation efficiency, fungal mutualist colonization, and miR408-mediated regulation. Localisation evidence places the product in the nucleus, cytosol and cytoplasm. Studies of related genes in other species connect the family to salt tolerance, bacterial blight disease resistance, resistance to Sclerotinia sclerotiorum, potato virus X resistance, and yield and root morphology traits.
Annotations
- Chromosome
- 2
- Related genes
- AGO2, AGO3
- GO terms
- homeostasis, RNA Processing, RNP, Regulation Of Translation, RNA-dependent gene silencing, Response To Jasmonic Acid, RNA Binding, Cytoplasm
- Publications
- 23313553, 21467580, 20935067, 26355083, 27534791, 23847649, 28432338, 18508405
- Traits
- extracellular RNA secretion and stabilization, RNA secretion, DNA repair, antiviral resistance, virus resistance, DNA methylation, RNA metabolism, DNA damage response