SHD — Nicotiana attenuata

Summary

A4A49_35071 (SHD, NaSHD) in coyote tobacco (Nicotiana attenuata) encodes a heat shock protein 90 (HSP90) family member, containing Hsp90 and HATPase domains, and is annotated with ATP-dependent protein folding chaperone activity. This gene is associated with a wide range of biological processes, including cellular response to unfolded protein, viral translation, respiratory burst involved in defense response, and double-strand break repair. It is linked to numerous traits such as floral organ morphology, seed set percent, bacterial and viral disease response, submergence tolerance, temperature stress response, and aphid response. Localization evidence connects the product to the chloroplast outer membrane, ER lumen, and Tic complex. Studies of related genes in other species link the HSP90 family to thermotolerance, broad-spectrum disease resistance, and salinity tolerance.